GR FOR DUMMIES

One nucleotide polymorphism that replaces A with G with the nucleoside 3669 (A3669G) located in the 3’ finish of exon 9b has become described in a ecu populace (461). This polymorphism does not change the amino acid sequence but boosts the balance of GRb mRNA and boosts GRb protein expression, leading to bigger inhibition of GRa-induced transcrip